SFTPC and pulmonary fibrosis: The goal of this study was to comprehensively ascertain differences in trafficking and posttranslational processing between WT and disease-associated SP-C mutants using doxycycline-inducible mouse lung epithelial cell lines expressing either WT SP-C or the common clinical variant SP-C<sup>I73T</sup>, validated using primary AT2 cells isolated from a murine SP-C<sup>I73T</sup> pulmonary fibrosis model and induced pluripotent stem cell-derived human AT2 cells expressing the same mutant.