TGFB1 and multiminicore myopathy: Cell interaction analysis highlighted the role of Mono_CD14_CD16 cells in mediating immune responses through interactions involving RETN and TGF-β signaling pathways.<h4>Conclusions</h4>This study provides a comprehensive analysis of peripheral immune cell alterations in MMD, highlighting the involvement of monocyte subpopulations and specific signaling pathways in disease pathogenesis.