Especially, complex 4-(OCH<sub>2</sub>CH<sub>2</sub>OCH<sub>2</sub>CH<sub>2</sub>OCH<sub>3</sub>)C<sub>6</sub>H<sub>4</sub>C[triple bond, length as m-dash]CAuPPh<sub>3</sub> (1d) displayed strong anticancer activity toward both cancer cells due to the strong inhibition of thioredoxin reductase (TrxR). This evidence concerns the gene PRDX5 and cancer.