The role of the choroid plexus in the development of brain dysfunction in hypoglycemia has not been sufficiently studied.<h4>Objective</h4>The aim of this work was to determine the structure of the choroid plexuses of the lateral ventricles of the brain during recurrent hypoglycemia.<h4>Materials and methods</h4>The object of the study were rats that had undergone 9 hypoglycemic states after insulin administration (with an interval of 3 days, the blood glucose level of 1.4-1.8 mmol/L) and intact animals. Here, INS is linked to Hypoglycemia.