Furthermore, WHO grade 2/3 meningiomas (p = 0.012), perioperative seizures (p = 0.024), subtype (p = 0.016), tumor laterality (p = 0.04), higher MIB-1 index (p < 0.001) and tumor volume (p = 0.01) were also significantly associated with PTBE. This evidence concerns the gene MIB1 and neoplasm.