In addition to well-established clinical, radiological, and histopathological risk factors, molecular markers such as Forkhead Box C1 (FOXC1) may also play a crucial role in the development of PTBE.<h4>Methods</h4>We conducted a retrospective, single-center study including 86 patients with histopathologically confirmed meningiomas. This evidence concerns the gene FOXC1 and meningioma.