RAF1 and rheumatoid arthritis: Conversely, the mQTL effect size at the cg26432171 site of the RAF1 (OR = 1.17, 95% CI [1.02-1.33]) is positively associated with RA risk and is consistent with the upregulation of gene expression (OR = 1.83, 95% CI [1.49-2.25]), thereby enhancing RA susceptibility.