Besides, cell culture supernatant was collected to detect the changes of IL-6, IL-10 and IL-17 levels.<h4>Results</h4>We found that in SLIT group, asthma symptom and drug use score, Th17 cell percentages, IL-6 and IL-17 levels have significantly decreased throughout the study period (p < 0.05), while FEV1%, Treg cell percentages and IL-10 level have prominently increased throughout the study period (p < 0.05). The gene discussed is IL10; the disease is asthma.