IGHE and combined immunodeficiency: Deceased patients showed significantly lower baseline platelets (183,000 vs. 266,000 cells/μL; P = 0.009), IgG (380 vs. 720 mg/dL; P = 0.007), and IgE (0.8 vs. 12 IU/mL; P = 0.008).<h4>Conclusion</h4>Pulmonary manifestations affect 81.1% of Iranian CID patients.