Logistic regression was performed to identify significant predictors, and the optimal cut-off value was established through receiver operating characteristic (ROC) analysis.<h4>Results</h4>The median serum CGRP level in patients with RA (91.1 pg/mL) was significantly higher than that of the control group (40.8 pg/mL) (P < .001). Here, CALCA is linked to rheumatoid arthritis.