Clinically however, a pre-surgical trial of green capsule vs. no green capsule in postmenopausal breast cancer patients with ductal carcinoma in situ (DCIS) or early-stage (I/II) invasive breast cancer, indicated a decline in cell proliferation (Ki-67) for women taking green tea supplements, but no significant changes were observed in apoptosis or angiogenesis. Here, MKI67 is linked to ductal breast carcinoma in situ.