As shown in immune cell infiltration analysis using CIBERSORT, MCPcounter, and TIMER algorithms, the CSRS score was negatively correlated with the infiltration of plasma cells and γδ T cells, while it demonstrated a positive correlation with the infiltration of CD4+ T cells, cancer-associated fibroblasts, endothelial cells, neutrophils, activated NK cells, monocytes and macrophages (Figure 6C–E). This evidence concerns the gene CD4 and cancer.