Hepatocellular carcinoma upregulated EZH2-associated lncRNA, or HEIH, is highly expressed in TNBC and can inhibit the JAK-STAT signaling pathway by “sponge adsorption” of miR-4458, upregulating the expression of suppressor of cytokine signaling (SOCSI), which ultimately inhibits apoptosis and promotes the proliferation of breast cancer cells [135]. The gene discussed is EZH2; the disease is breast cancer.