No significant correlation was found between CRHR1 gene Exon1/210/(p = 0.77), Exon 1/229/(p = 0.57), Exon 8 (p = 0.74), Exon 11 (p = 0.91), and Exon 14 (p = 0.9) CNVs and perceived cognitive issues, suggesting that self-reported cognitive impairment may not be directly influenced by genetic variations (Figure 3). This evidence concerns the gene CRHR1 and Cognitive impairment.