NPPB and cardiovascular disorder: Additionally, it has been proposed that in addition to cardiac troponin (cnTI, hs-cTnT), brain natriuretic peptides (BNP, NT-pro-BNP), C-reactive protein (CRP, hs-CRP), and lactate dehydrogenase (LDH) [15,16], UA should be used as an auxiliary biomarker for early identification of cardiovascular diseases to reduce the cost of identifying high-risk patients [17].