In TSH-, ACTH-, and LH-secreting PitNETs, tumor cell proliferation was not correlated with VEGF expression (p = 0.262, p = 0.745, and p= 0.250, respectively) nor with hormone levels (p = 0.181, p = 0.986, and p = 0.324, respectively). This evidence concerns the gene POMC and neoplasm.