Keywords were combined using Boolean operators and encompassed: “colorectal cancer”, “colorectal neoplasia”, “early detection strategies”, “diagnostic pathways”, “colonoscopy”, “FIT”, “stool DNA testing”, “molecular biomarkers”, “p53”, “PTEN”, “ctDNA”, “circulating tumor cells”, “liquid biopsy”, “multi-omics”, “artificial intelligence”, and “Poland”. The gene discussed is TP53; the disease is neoplasm.