On the other hand, they showed that HLA-DQA1*01:02, HLA-DPB1*01:01, HLA-B*58:01, HLA-B27, HLA-B51, and HLA-B57 are protective alleles for HIV disease progression to AIDS, while the haplotype DRB1*03:01-DQA1*05:01-DQB1*02:01 is associated with disease progression. The gene discussed is HLA-DRB1; the disease is AIDS.