Finally, we predicted the top 50 target genes related to IDD, with the top 10 target genes being Sod2, Cxcl12, Spp1, Fn1, Cat, Il6, Ccl2, Igf1, Fgf2, and Acta2 (Figure 7C). This evidence concerns the gene ACTA2 and intervertebral disk degenerative disorder.