To resolve this discrepancy, our analysis of the CCLE database pointed towards a context-dependent role for ZNF668, as we found its expression was significantly higher in cell lines of mesenchymal origin (e.g., SARC, GBM, LAML) compared to those from many epithelial cancers (e.g., HNSC, ESCA). The gene discussed is ZNF668; the disease is glioblastoma.