TOP2A and meningococcal infection: BACKGROUNDDual penicillin- and ciprofloxacin-resistant <i>Neisseria meningitidis</i> causing invasive meningococcal disease (IMD) have recently emerged in association with sequence type (ST) 3587, harbouring ROB-1 β-lactamase (<i>bla</i> <sub>ROB-1</sub>) and a mutated DNA gyrase (<i>gyrA</i>).