SELENOP and diabetes mellitus: We previously linked excessive selenoprotein P (SeP, encoded by SELENOP in humans) to pathological conditions frequently observed in individuals with diabetes.<h4>Objective</h4>The present study aimed to clarify the role of SeP in the metabolic stress-induced anxiety.<h4>Methods</h4>We visualized Selenop expression in the mouse brain section via RNAscope in situ hybridization and used RT-qPCR to evaluate gene expression in brain regions.