Notably, these unedited and/or under-edited dsRNAs appeared as filament-like structures were detected by immunostaining using J2 mAb specific to unedited dsRNA in mouse Yumm1.7 cutaneous melanoma (CM) cells treated with ADAR1 inhibition-positive compounds, ADAR1i-13, ADAR1i-120, and ADAR1i-124, but were absent in cells treated with ADAR1 inhibition-negative compounds (Figure 2A). This evidence concerns the gene ADAR and cutaneous melanoma.