Dysregulated autophagy is known to have a role in the pathogenesis of ovarian cancer, and disruption of autophagy regulators like LC-3BII, p62, autophagy related 5 (ATG5), Beclin1 and unc-51 like kinase 1 (ULK1) induces ovarian cancer via promoting cellular growth and preventing autophagosome formation (64). The gene discussed is ATG5; the disease is ovarian cancer.