IFNB levels remain low in P’s SV40-fibroblasts, at ∼1/5 of its levels in healthy controls’ cells, at baseline or following HSV-1 infection at a multiplicity of infection (MOI) of 1 for 8 h (Fig. 3 C), whereas IFNB levels became about twice higher in P1’s cells than that of the healthy controls likely due to the enhanced HSV-1 replication levels in P1’s cells at this time point. Here, IFNB1 is linked to infection.