NDUFB3 and fibrosis: Our findings highlighted a number of NF-κB1 targets known for their role in establishing an inflammatory environment in the bone marrow fibrotic niche (Figure 3B),11,22 among them IL18, S100A8/S100A9, NDUFB10, and NDUFB3. Specifically, the distinct IL-18 expression peaking at grade 2 of reticulin fibrosis caught our attention (Figures 3B and 1F).