Under the acute phase reactant category, Calgranulin-C (S100A12) is reported to have AUC 0.77 with 96% sensitivity and 56% specificity to discriminate between Medical NEC and the controls, followed by AUC of 0.81 with 74% sensitivity and specificity to discriminate between Surgical NEC and the controls. This evidence concerns the gene S100A12 and necrotizing enterocolitis.