•Reduced the expression of NF-κB p65 protein in human ovarian cancer cells (A2780) at 2 μM.•Reduced IL-1β (p < 0.01) from approximately 14 to between 11 and 12 pg/mL, IL-8 from approximately 85–45 pg/mL and TNF-α (p < 0.0001) from approximately 14–18 pg/mL at 0.02 μM when compared to lipopolysaccharide (LPS) simulated human keratinocyte (HaCaT) cells. This evidence concerns the gene TNF and ovarian cancer.