Conversely, in pancreatic cancer, increased abundance of anaerobic bacteria (including Bacteroides, Lactobacillus, and Peptostreptococcus) is linked to diminished CD4+, CD8+, and CD45RO+ tumor-infiltrating lymphocytes, as well as an overall poorer prognosis (Abe et al., 2024). Here, CD8A is linked to neoplasm.