GCG and type 1 diabetes mellitus: Notably, T1D participants receiving amino acids still had a significant elevation in peak glucagon levels (124 ± 25 ng/L) compared to placebo (49 ± 9 ng/L), thereby confirming that individuals with T1D can have a robust glucagon response to protein intake even if their glucagon counterregulatory response to hypoglycemia is blunted (33).