IL6 and infection: For example, as observed in humans, rhesus macaques, and murine models, IL-6—which was sixfold higher in KETRI 3801 than in KETRI 3928 infections at 12 dpi (Figure 4E)—can, in a reversible and dose-dependent manner (van Gameren et al., 1994; Winton et al., 1994; Neves et al., 2021), reduce serum iron levels (Neves et al., 2021), thereby suppressing erythropoiesis.