To further understand the specific role of miR-221/222-3p in regulating cancer, the expression of five experimental validated target genes (CDKN1C, KIT, ICAM1, SSX2IP, and TNFSF10) from the miRTargetLink Human database (Figure 5) among several previous cancers was calculated via the ‘GEPIA’. The gene discussed is TNFSF10; the disease is cancer.