To further understand the specific role of miR-221/222-3p in regulating cancer, the expression of five experimental validated target genes (CDKN1C, KIT, ICAM1, SSX2IP, and TNFSF10) from the miRTargetLink Human database (Figure 5) among several previous cancers was calculated via the ‘GEPIA’. This evidence concerns the gene CDKN1C and cancer.