Gender, hepatitis B, TC, and AT3 constitute risk factors for hepatocellular carcinoma in cirrhotic patients; Gender, hepatitis type, DOI, FT4, AT3, SCC, CRP, MAO, and Ca are associated with the progression of liver cirrhosis to malignant liver tumours either directly or indirectly. Here, SERPINC1 is linked to hepatocellular carcinoma.