PPARA and systemic lupus erythematosus: KEGG analysis indicated associations with intestinal immune networks for IgA production, hematopoietic cell lineage, B cell receptor signaling, and cytokine-cytokine receptor interaction, while GSEA demonstrated enrichment in complement and coagulation cascades, ECM-receptor interaction, focal adhesion, PPAR signaling, ribosome biogenesis, primary immunodeficiency, and systemic lupus erythematosus-related pathways.