In lipid metabolism, its high expression indirectly supports lipid synthesis and metabolism by maintaining cell cycle progression; for instance, in pancreatic adenocarcinoma, inhibition of CDC25C impairs mitochondrial respiratory function and increases reactive oxygen species (ROS) accumulation (39), suggesting that it may affect the energy supply for lipid metabolism by regulating mitochondrial homeostasis. Here, CDC25C is linked to pancreatic adenocarcinoma.