In contrast, HMMR, KPNA2, and PALB2 were significantly overexpressed in tumor tissues relative to normal counterparts (p < 0.0001), while CDC25C showed significant overexpression with a slightly lower statistical significance (p < 0.001) and TKT exhibited a significant overexpression at a moderate level (p < 0.05) (Figures 9A-F). The gene discussed is PALB2; the disease is neoplasm.