Deoxyribonuclease I (DNase I, EC 3.1.21.1), isolated from bovine pancreas, is an enzyme used for treating MDR pathogen infections by cleaving the 3′,5′-phosphodiester bond of biofilm-associated extracellular DNA.76–78 Biofilms having extracellular DNA (E-DNA) are present in various species such as Streptococcus mutans, Bordetella pertussis, Enterococcus faecalis, Streptococcus pneumoniae, Listeria monocytogenes, Campylobacter jejuni and Staphylococcus epidermidis. Here, DNASE1 is linked to infection.