Further research can combine in vivo imaging with histological analysis in efficacy models, such as HSV-1 infection or allergic rhinitis, to determine which cells of the innate immune system have direct contact with hDLE peptides and whether the effect is also amplified by cellular pathways, in addition to the already known humoral pathways (IFN-ɣ, TNF-α, IL-6). The gene discussed is TNF; the disease is allergic rhinitis.