AD, the most prevalent neurodegenerative disorder (Świetlik et al., 2022), is characterized by the accumulation of amyloid-β (Aβ) plaques and hyperphosphorylated tau, leading to neuronal dysfunction, inflammation, and oxidative stress in the central nervous system (Halawani et al., 2010; Rohn and Head, 2009). The gene discussed is MAPT; the disease is Alzheimer disease.