Mutation in the α1 subunit of the L-type voltage-gated calcium channel Cav1.3, activating Ca2+ at reduced depolarization potentials, leading to increased Ca2+ influx and overexpression of CYP11B2 (67).Early onset, at birth, or usually before age 10 years old. Featuring neuromuscular abnormalities (PASNA—Primary Aldosteronism associated with Seizures and Neurologic Abnormalities) (67). Here, CYP11B2 is linked to Seizure.