Furthermore, LBP activated intestinal mucosa Toll-like receptor 2 (TLR2) intraepithelial γδ T cells and upregulated intestinal tight junctions (TJs) such as zonula occludens-1 (ZO-1) and occludin, potentially repairing the intestinal barrier and inhibiting enteral and parenteral inflammation, ultimately improving DM-related biochemical abnormalities (64). The gene discussed is LBP; the disease is diabetes mellitus.