Data analyses indicated that HbA1c was strongly and positively correlated with fasting plasma glucose (r = 0.532, p < 0.001) and moderately correlated with HOMA-IR (r = 0.371, p < 0.001) and fasting insulin (r = 0.188, p = 0.019), suggesting a close association between glycemic burden and underlying insulin resistance. Here, INS is linked to Insulin resistance.