Compared with patients in Hurley stages I–II, those with Hurley stage III had higher TP (OR, 1.171; 95% CI, 1.087–1.262; q = 0.0001), but lower albumin (OR, 0.880; 95% CI, 0.794–0.975; q = 0.033), ALT (OR, 0.980; 95% CI, 0.965–0.996; q=0.028), AST (OR, 0.953; 95% CI, 0.918–0.989; q=0.022), and TB (OR, 0.896; 95% CI, 0.824–0.974; q=0.028). The gene discussed is ALB; the disease is tuberculosis.