This research aimed to determine the predictive value of a combined diagnosis of serum platelet endothelial cell adhesion molecule-1 (PECAM-1) and placental growth factor (PLGF) levels, gut microbiota count, and uterine artery Doppler ultrasonography in relation to pregnancy outcomes in patients with hypertensive disorders complicating pregnancy (HDCP). The gene discussed is PGF; the disease is hypertensive disorder.