Our cytokine analysis revealed that pediatric non-T2 asthma is characterized by elevated Th1 and Th17 cytokines, including IL-2, IL-6, IFN-γ, and IL-17A, accompanied by the downregulation of immunoglobulin-associated genes, indicating an attenuated Th2 signature and reduced atopy (20). This evidence concerns the gene IFNG and asthma.