Using CIBERSORT-derived immune deconvolution, we observed significant differences in the immune cell abundances across the AP severity categories (naive B cells, plasma cells, CD8+ T cells, resting CD4+ memory T cells, follicular helper T cells, γδ T cells, resting NK cells, resting mast cells, and neutrophils; p < 0.05) (Figure 10A). The gene discussed is CD8A; the disease is alkaline phosphatase measurement.