ITGB3 and familial pancreatic carcinoma: Analysis using the Xiantao online tools revealed that the CD274 (PD-L1) gene exhibits high expression levels in tumor samples from hepatocellular carcinoma, pancreatic cancer, renal cancer, and urothelial cancer, alongside elevated expression of αv (ITGAV) and β3 (ITGB3) genes (Figure 1A).