ALS male (Figures 10C,C’) and female (Figures 10F,F’) mice receiving ApoA1 demonstrated robust appearing motor neurons with significantly (p < 0.01) higher motor neuron numbers (males: 35.33 ± 3.12%; females: 30.34 ± 1.92%) compared to media mice (Figure 10G). Here, APOA1 is linked to amyotrophic lateral sclerosis.