In an experimental autoimmune encephalomyelitis model, which mimics inflammatory demyelination observed in multiple sclerosis, adult female C57BL/6 J mice were immunized with myelin oligodendrocyte glycoprotein (MOG35–55) and killed Mycobacterium tuberculosis and treated daily with R-ketamine from 30 min before immunization to day 14 (Wang et al., 2021). This evidence concerns the gene MOG and experimental autoimmune encephalomyelitis.