As indicated in Table 1, elderly patients with Major Depressive Disorder (MDD) and lipid metabolism abnormalities exhibited higher Body Mass Index (BMI), Hamilton Depression Rating Scale (HAMD) scores, Hamilton Anxiety Rating Scale (HAMA) scores, Positive and Negative Syndrome Scale (PANSS) positive subscale scores, Thyroid Stimulating Hormone (TSH) levels, Thyroglobulin Antibody (TG-Ab) levels, and fasting blood glucose levels compared to patients without lipid metabolism abnormalities. The gene discussed is TG; the disease is depressive symptom measurement.