TNF and hematoma: Figure 5A illustrates the anatomical regions analyzed, with colored areas indicating distinct brain areas affected by the autologous blood injection (more detailed tissue section images are available in the original publications (Xiang et al., 2025)). Spatial expression analysis (Figure 5B) revealed temporally regulated patterns showing significantly elevated expression of Hspa5, Hk2, and Tnf surrounding the hematoma region (left hemisphere) compared to the contralateral side (right hemisphere) across several timepoints.