The positive control reduced IL-6 to 95.0 ± 8.4 pg/mL (*** p < 0.001 vs. model), whereas AF-SD further lowered IL-6 to 95.33 ± 7.2 pg/mL, representing a 49.56% reduction (*** p < 0.001 vs. model) and remaining significantly lower than the positive control (** p < 0.01). The gene discussed is IL6; the disease is atrial fibrillation.